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Epub Nov 2. Electronic address: c. Abstract The discovery of genetic drivers of lung cancer in patient sub-groups has led to their use as predictive biomarkers and as targets for selective drug therapy.

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The Long Knives Are Crying. To investigate the risk factors for breakthrough vitreous hemorrhage VH after intravitreal anti-vascular endothelial growth factor anti-VEGF injection in age-related macular degeneration AMD accompanied by submacular hemorrhage SMH. We retrospectively reviewed the medical records of patients diagnosed with AMD combined with SMH, and enrolled 31 patients.

We formed an age- and sex-matched control group of patients with submacular hemorrhage who did not develop breakthrough VH after intravitreal injection during 6 month follow-up.

The mean patient age was Of the 31 patients, 8 were diagnosed with choroidal neovascularization CNV , 22 with polypoidal choroidal vasculopathy PCV , and 1 with retinal angiomatous proliferation RAP. PCV was associated with a significantly higher incidence of VH odds ratio, The size of the SMH was There was no significant difference between the types of anti-VEGF agents.

National Center for Biotechnology Information , U.